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Alteplase (tPA) thrombolytic agent

Fibrinolytic agent

Image of Alteplase (tPA) thrombolytic agent

Three-panel learning framework

Recognition, context, and distinction

01

What am I looking at?

Visual recognition

Reconstituted tPA vial or syringe instilled into the catheter lumen or lytic infusion circuit.

02

What does it do, and where will I see it?

Use & procedural context

Provides fibrinolytic therapy by converting plasminogen to plasmin and promoting clot dissolution. In IR, alteplase is used for catheter declotting and catheter-directed thrombolysis of dialysis-access, venous, and selected arterial thromboses.

03

What most clearly distinguishes it from similar devices?

Key distinctions

Alteplase is a thrombolytic medication rather than a mechanical thrombectomy device; it may be infused through a catheter or used to declot an access device when pharmacologic fibrinolysis is intended.